How to bid on a Technology Licensing Opportunity: Nanofet from Department of Energy

What the agency is buying and why a vendor would care

The Department of Energy, through Los Alamos National Laboratory (LANL), is offering licensing opportunities for its NanoFiber Engineered Therapeutics Platform (NanoFET). This platform is a modular nanofiber scaffold designed for developing immunotherapies, vaccines, and biodefense treatments. It uses interchangeable nanobodies and peptides, supports multivalent targeting, and is at technology readiness level 3.

This opportunity is for companies interested in licensing an existing, advanced technology rather than providing development services. It could be valuable for pharmaceutical, biodefense, and biotechnology firms looking to enhance their product lines with a versatile and innovative therapeutic platform.

Key dates and what happens at the deadline

This licensing opportunity was published on June 17, 2026. The deadline for expressing interest is December 17, 2026, at 7:00 PM ET. At the deadline, LANL will stop accepting new inquiries or expressions of interest for licensing this specific technology. It is important to submit any licensing proposals or contact the agency before this date.

Who this opportunity suits

This opportunity is suitable for existing pharmaceutical companies, biotechnology firms, and startups in the professional category, particularly those focused on oncology, infectious disease therapeutics, biodefense, military medicine, vaccine development, and drug delivery. Firms with expertise in biologics, immunotherapy, and nanotechnology will find this technology relevant. This is not a request for proposals for external development services, but rather an invitation to license an already developed technology.

How to respond

To access the original source for this opportunity, click the “View original source” button. If the first click takes you to the portal’s homepage, click it again to go directly to the bid. You may need to create a free account to view all documents, though this is not always required. For specific discussions about licensing, you should contact [email protected] as indicated in the full description.

Practical tips for preparing a competitive response

When preparing to license a technology like NanoFET, thoroughly review the patent application details (U.S. patent application LA-UR-26-25007) and understand the technology readiness level (TRL 3). Clearly articulate your company's business plan for commercializing this technology, including market analysis, development roadmap, and financial projections.

Highlight your company's relevant experience, existing infrastructure, and access to capital that would support the successful integration and deployment of NanoFET. Emphasize how your firm's capabilities align with the stated market applications, such as oncology or biodefense, and how you plan to leverage the modularity and other advantages of the platform. Be prepared to discuss whether you are seeking an exclusive or non-exclusive license and justify your preference.