Bid guide
How to bid on SHINE Targeted Neuroplasticity Research for DARPA
What DARPA is buying and why it matters
The Defense Advanced Research Projects Agency (DARPA) is looking for innovative basic or applied research concepts related to targeted neuroplasticity. This initiative is called the Selective Harnessing of Intrinsic Neuroplasticity Engineering (SHINE) Disruption Opportunity.
Successful proposals will be awarded as Other Transaction (OT) prototype agreements. Each award is capped at $2,000,000, which includes both government funding and any required or proposed cost share from the performer. This is a chance for firms to contribute to advanced defense science research.
Key dates and what happens at the deadline
This opportunity was published on August 28, 2026. The deadline for submissions is October 09, 2026, at 12:00 PM ET. All proposals must be submitted by this exact time.
It is important to submit your response well before the deadline to avoid any last-minute technical issues. Late submissions are typically not accepted.
Who this opportunity suits
This opportunity is best suited for firms and research organizations with expertise in professional services, specifically in basic or applied research within the technical domain of targeted neuroplasticity. If your firm has innovative concepts in this area, this could be a good fit.
The solicitation is issued under the Program Announcement for Disruptioneering, DARPA-PA-25-07 Amendment 1, indicating a focus on disruptive scientific advancements.
How to respond to this solicitation
To access the full details and respond, you need to view the original source on the portal. Click the designated link to open the opportunity. If the first click takes you to the portal's homepage, click the link again to go directly to the bid.
You may need to create a free account on the portal to view all associated documents. For some bids, an account is not necessary to view documents, but it is good practice to be prepared.
Tips for preparing a competitive response
Ensure your research concept is clearly innovative and directly addresses targeted neuroplasticity as specified by DARPA. Highlight the potential impact and scientific merit of your proposed work.
Carefully review the requirements for Other Transaction prototype agreements, including any cost share expectations. Clearly articulate how your proposed budget aligns with the $2,000,000 award limit. Provide a detailed and realistic project plan, outlining your methodology, expected outcomes, and timelines.
See the live bid — deadline, agency details, and how to respond
Dates and requirements can change via addenda; always verify on the bid page and at the original source before responding.
View this bid on BiddingSimpleThis guide was prepared by BiddingSimple from the solicitation’s public posting. It is not official guidance from Defense Advanced Research Projects Agency (DARPA); the original posting controls.