How to bid on HUBBLE protein-interaction research for DARPA

What DARPA is seeking

DARPA is seeking proposals to develop an in-silico capability for mapping protein-protein interactions. The capability will be demonstrated by identifying novel diagnostic and therapeutic targets in the interaction space, including targets related to traumatic brain injury.

This RFP may interest firms and research teams working on computational biology, protein interactions, or related areas of professional services.

Deadline and what it means

Proposals are due November 5, 2026, at 3:00 p.m. Eastern Time. The opportunity was published October 8, 2026.

Plan to submit before the stated deadline. The provided information does not specify what happens to late proposals.

Who this opportunity suits

This opportunity is suited to organizations able to develop a computer-based approach to mapping protein-protein interactions and demonstrate its usefulness for identifying diagnostic or treatment targets. The listed category is professional.

How to access the opportunity

Click “View original source” above to open the opportunity on the portal. If the first click takes you to the portal homepage, click it again to go to the bid.

A free account may be needed to view documents, though some bids can be viewed without one.

Prepare a focused proposal

Explain clearly how your proposed capability will map protein-protein interactions and how you would demonstrate its value in identifying diagnostic and therapeutic targets, including targets related to traumatic brain injury.

Review the solicitation documents for the required proposal format and submission instructions. Make sure your response addresses the stated requirements, and leave time to complete submission before the deadline.