Bid guide
How to bid on Chemical, Biological, Radiological and Nuclear Advance Defense Enabling Network and Clinical Capability (CADENCC) for the DEPT of Defense
What the Department of the Army is buying
The Department of the Army is seeking proposals to develop the Chemical, Biological, Radiological and Nuclear Advance Defense Enabling Network and Clinical Capability (CADENCC). This project aims to speed up clinical trial startup for chemical, biological, radiological, and nuclear defense products.
The work involves using master protocols, decentralized trial technologies, and improved data collection and analysis. It also includes establishing a ready network of clinical trial sites, primarily for Phase I and II trials. This is a prototype project under Other Transaction Authority (OTA).
Key dates and what happens at the deadline
This Request for Project Proposal (RPP) was issued on September 03, 2026. Preproposals are due by 3:00 PM ET on September 17, 2026.
After the deadline, the Government will evaluate submitted preproposals. If there is interest, discussions may occur, and the Government may request a full proposal. An award may be made after evaluation and selection, depending on fund availability.
Who this opportunity suits
This opportunity is suitable for organizations with expertise in clinical trial acceleration, master protocols, decentralized trial technologies, and data collection and analysis for clinical trials. Firms with experience in chemical, biological, radiological, and nuclear defense readiness, particularly for Phase I and II trials, would be well-suited.
Organizations must be registered in SAM to be eligible for this prototype project under Other Transaction Authority.
How to respond
To access the opportunity, click “View original source” on the portal. If you land on the homepage, click it again to go directly to the bid. You may need a free account to view documents, though this is not always required.
The RPP requests formal submission of preproposals. Follow the instructions within the RPP for preparing and submitting your preproposal by the deadline.
Tips for preparing a competitive response
Clearly demonstrate your understanding of the project's objective: accelerating clinical trial startup for CBRN defense. Highlight your capabilities in implementing master protocols and utilizing innovative decentralized trial technologies.
Emphasize your experience with Phase I/Phase II clinical trials and your ability to establish or leverage a pre-positioned clinical trial site network. Ensure your preproposal directly addresses the requirements outlined in the Statement of Objectives (SOO) mentioned in the RPP. Since this is a prototype project under Other Transaction Authority, focus on the innovative aspects and military utility of your proposed solution.
See the live bid — deadline, agency details, and how to respond
Dates and requirements can change via addenda; always verify on the bid page and at the original source before responding.
View this bid on BiddingSimpleThis guide was prepared by BiddingSimple from the solicitation’s public posting. It is not official guidance from DEPT of the Army; the original posting controls.