Bid guide
How to bid on Chemical, Biological, Radiological and Nuclear Advance Defense Enabling Network and Clinical Capability (CADENCC) for the Department of the Army
What the Army is buying and why it matters
The Department of the Army is seeking prototype proposals for the Chemical, Biological, Radiological and Nuclear Advance Defense Enabling Network and Clinical Capability (CADENCC). This project aims to develop a clinical trial capability for chemical, biological, radiological, and nuclear (CBRN) defense.
The work involves accelerating clinical trial startup through master protocols, using innovative technologies for decentralized trial operations, improving data collection and analysis, and establishing a pre-positioned clinical trial site network. CADENCC will primarily conduct Phase I and Phase II clinical trials for pre-exposure prophylaxis, post-exposure prophylaxis, and early treatment products. This is an opportunity to contribute to critical national defense readiness.
Key dates and what happens at the deadline
Preproposals are due by September 17, 2026, at 3:00 PM Eastern Time. This is a firm deadline.
After the deadline, the Government will evaluate submitted preproposals. If there is Government interest, the Agreements Officer may issue a request for a full proposal. Discussions may occur at various stages, and an award may be made after evaluation and selection, dependent on funding availability.
Who this opportunity suits
This opportunity is suitable for firms with expertise in clinical trial development, particularly those with experience in Phase I and Phase II trials, decentralized trial operations, and advanced data collection and analysis. Experience with chemical, biological, radiological, and nuclear defense products or related medical solutions is highly relevant.
The solicitation is for a prototype project under Other Transaction Authority (OTA), which often suits companies that can bring innovative technologies and approaches to complex problems.
How to respond
To access the full details and prepare your response, you must first view the original source on the portal. Click the “View original source” link. If the first click takes you to the portal’s homepage, click the link again to go directly to the bid.
You may need to create a free account on the portal to view all documents, though this is not always required for every bid. Ensure you are registered in SAM.gov, as this is a requirement before any award can be made.
Tips for preparing a competitive response
Focus your preproposal on clearly demonstrating your capability to meet the objectives outlined, especially regarding accelerating clinical trial startup, supporting decentralized operations, and enhancing data handling. Highlight any experience with Master Protocols or establishing clinical trial networks.
Since this is for a prototype project under Other Transaction Authority, emphasize innovative approaches and how your proposed solution directly enhances the mission effectiveness of the Department of Defense personnel in CBRN defense. Clearly articulate the technical or manufacturing feasibility and military utility of your proposed technology or process.
See the live bid — deadline, agency details, and how to respond
Dates and requirements can change via addenda; always verify on the bid page and at the original source before responding.
View this bid on BiddingSimpleThis guide was prepared by BiddingSimple from the solicitation’s public posting. It is not official guidance from DEPT of the Army; the original posting controls.