How to bid on BARDA Drive EZ-BAA (EZBAA - 22-100-SOL-00003) from ASPR

What the agency is buying

The Office of Assistant Secretary for Preparedness and Response (ASPR) is seeking research and development proposals in biotechnology. This includes areas such as diagnostics, therapeutics, and vaccines. This solicitation, known as the BARDA DRIVe EZ-BAA, is a reissuance and supersedes previous versions.

Currently open areas of interest include "Lab at Home," "Healing Lungs," and "Agnostic Diagnostic." These topics are subject to frequent updates, with new areas added and existing ones revised or paused. Vendors should review the latest information to understand the specific needs and opportunities.

Key dates and deadlines

This solicitation was published on April 22, 2025. The overall deadline for proposals is October 18, 2027, at 4:30 PM ET. However, individual Areas of Interest (AOIs) within this broad agency announcement have their own specific closing dates, which are frequently updated through amendments.

It is critical for interested parties to consult the attached amendments and the official BARDA DRIVe website for the most current closing dates for each specific research area. Missing an AOI's specific deadline will result in your proposal not being considered for that particular topic.

Who this opportunity suits

This opportunity is suitable for firms engaged in professional services, particularly those with expertise in biotechnology research and development. Companies specializing in diagnostics, therapeutics, and vaccine development will find relevant areas of interest.

Given the nature of the topics, organizations with strong scientific research capabilities, laboratory resources, and experience in developing medical countermeasures are well-suited to respond.

How to respond

To access the solicitation details, you must first click the "View original source" link on the portal. If the first click takes you to the portal's homepage, click the link again to go directly to the bid.

You may need to create a free account on the portal to view all associated documents. Review the main announcement and all subsequent amendments carefully, as these provide crucial updates on open areas of interest, revisions, and specific closing dates for each topic. Also, visit the drive.hhs.gov website for the most current information.

Practical tips for a competitive response

Given the dynamic nature of this Broad Agency Announcement (BAA), regularly check for new amendments. Each amendment can introduce new areas of interest, revise existing ones, or update closing dates, which directly impacts your proposal strategy.

Focus your proposal on a specific Area of Interest (AOI) that aligns with your firm's core competencies and research capabilities. Clearly articulate how your proposed solution addresses the specific needs outlined in that AOI. Ensure your technical approach is sound and demonstrates a clear path to achieving the desired outcomes.

Pay close attention to any specific submission instructions or formatting requirements detailed in the solicitation and its amendments. A well-organized and compliant proposal increases your chances of a favorable review.