Bid guide
How to bid on Assay Service for assessing ADME and PK properties for HHS
What the agency is buying
The Department of Health and Human Services (HHS) needs a vendor to provide assay development and laboratory testing services. This includes performing grouped ADME (Absorption, Distribution, Metabolism, and Excretion) assays and a pharmacokinetic (PK) study in C57BL6 mice.
Specifically, the work involves Caco-2 permeability testing to assess compound permeability, transport, and oral absorption potential. These services are crucial for evaluating new molecular entities in drug development, helping HHS decide which compounds to advance for further development.
Key dates and what happens at the deadline
This opportunity was published on September 10, 2026. The deadline for responses is September 19, 2026, at 9:00 AM ET. All submissions must be received by this time.
It is important to submit your proposal well before the deadline to avoid any last-minute technical issues.
Who this opportunity suits
This solicitation is suitable for firms with expertise in healthcare and life sciences, specifically in drug discovery and development services. Vendors should have capabilities in conducting in vitro cell-based assays, such as Caco-2 permeability assays, and in vivo pharmacokinetic studies in animal models like C57BL6 mice.
The ideal vendor will have experience in assessing ADME properties and evaluating the translational potential of novel molecular entities.
How to respond
To access the full solicitation details and prepare your response, you need to go to the original source on the portal. Click the "View original source" link. If the first click takes you to the portal's homepage, click the link again to go directly to the bid.
You may need to create a free account on the portal to view all the documents, though for some bids, this is not required.
Tips for preparing a competitive response
Clearly demonstrate your firm's experience with both in vitro ADME assays, especially Caco-2 permeability testing, and in vivo pharmacokinetic studies in mice. Provide specific examples of similar projects you have successfully completed.
Highlight your understanding of the importance of these assays in drug development and how your services can help HHS make informed decisions on their novel molecular entities. Ensure your proposal directly addresses all requirements outlined in the solicitation, paying close attention to the technical specifications for each assay and study.
See the live bid — deadline, agency details, and how to respond
Dates and requirements can change via addenda; always verify on the bid page and at the original source before responding.
View this bid on BiddingSimpleThis guide was prepared by BiddingSimple from the solicitation’s public posting. It is not official guidance from National Institutes of Health; the original posting controls.