Opportunity timeline
In plain English
The Department of Energy is offering licensing opportunities for PAD-TIE, a platform developed by NREL and Los Alamos National Laboratory to screen tens of thousands of enzyme variants for breaking down PET plastic. The system evaluates enzyme activity, stability, and production potential under industrially relevant conditions and has been validated in lab-scale bioreactors. The technology is at readiness level 6, with three U.S. patents pending, and is available to existing and startup companies through exclusive or non-exclusive licensing agreements.
About this opportunity
NREL and Los Alamos National Laboratory’s PAD-TIE platform is an advanced screening system designed to accelerate the discovery and optimization of enzymes that break down polyethylene terephthalate (PET), one of the most widely used plastics. The Challenge: Traditional enzyme development is slow and requires testing individual enzymes under controlled conditions. PAD-TIE overcomes this limitation by simultaneously screening tens of thousands of enzyme variants under industrially relevant conditions for PET degradation. How it Works: Unlike conventional methods, PAD-TIE evaluates enzyme efficiency, stability, and production potential in a single process, ensuring that only the most viable…
Time remaining
Closes Oct 1, 2026
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Ref No.
BS-E8DF71

