Bid guide
How to bid on developing selective small-molecule inhibitors for NIH
What the NIH is buying and why it matters
The National Institutes of Health (NIH) is seeking commercial research services to develop selective small-molecule inhibitors. This is a firm-fixed-price opportunity, meaning the payment amount is set and does not change.
This contract offers a chance for businesses to contribute to important scientific research in the healthcare sector, specifically in biological product manufacturing. It is a direct opportunity to work with a federal agency on a defined project.
Key dates and what happens at the deadline
This solicitation was published on August 07, 2026. The deadline for proposals is August 24, 2026, at 8:00 AM ET. All proposals must be submitted by this time.
Late submissions may not be considered. The government intends to award a contract or purchase order to the offeror whose proposal represents the best value.
Who this opportunity suits
This opportunity is suitable for businesses involved in biological product manufacturing, specifically those with expertise in developing small-molecule inhibitors. The applicable NAICS code is 325414, Biological Product (except Diagnostic) Manufacturing.
This is an unrestricted, full and open competition, meaning businesses of any size can bid. The small business size standard for this NAICS code is 1,250 employees.
How to respond to this solicitation
To access the solicitation, you will need to click the “View original source” link on the portal. If the first click takes you to the portal’s homepage, click the link again to go directly to the bid.
You may need to create a free account on the portal to view all the documents. This solicitation is a combined synopsis/solicitation, and proposals are being requested directly from this announcement; a separate written solicitation will not be issued.
Tips for preparing a competitive response
Carefully review all parts of the solicitation, including any incorporated provisions and clauses, to ensure full compliance. Since this is a firm-fixed-price contract, clearly define your proposed services and costs.
Highlight your firm's experience and capabilities in developing small-molecule inhibitors. Emphasize how your approach offers the best value to the government, focusing on the quality and effectiveness of your proposed research services.
See the live bid — deadline, agency details, and how to respond
Dates and requirements can change via addenda; always verify on the bid page and at the original source before responding.
View this bid on BiddingSimpleThis guide was prepared by BiddingSimple from the solicitation’s public posting. It is not official guidance from Health and Human Services, Department of; the original posting controls.